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Genetic Risk Factors for Poor Cognitive Outcome Following Brain Insult-A Systematic Review.

Brain and behavior - 1 Jan 2026

Dunås Tora, Leiss Sophia, Corell Alba, Skoglund Thomas, Dénes Anna, Carén Helena, Smits Anja, Rydén Isabelle, Jakola Asgeir

Abstract excerpt

INTRODUCTION: Cognitive outcomes following brain insult are shaped by a range of factors, including genetic predispositions. Emerging evidence indicates that specific genetic variants may affect the susceptibility to cognitive impairment in individual patients. In this systematic review we summarize the evidence for genetic variants on cognitive outcomes following brain insults. METHODS: A systematic search was...

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Identifiers

PMID: 41476008
DOI: 10.1002/brb3.71173
PMCID: PMC12755970

Genes

APOE
COMT
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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