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Article

The role of N6-methyladenosine associated genes in ischemic stroke risk: interplay with environmental factors.

Journal of thrombosis and thrombolysis - 1 Apr 2026

Chiu Yu-Ching, Yi Ling, Zhang Yuqin, Hu Weihua, Bai Jianjun, Wu Wenjing, Wang Tong, Hao Yuantao, Yu Hongmei, Wang Xiaowen

Abstract excerpt

Ischemic stroke is a leading cause of morbidity and mortality worldwide, resulting from a complex interplay between genetic predisposition and environmental exposures. Recent advances have highlighted the importance of epitranscriptomic regulation, particularly N6-methyladenosine (m6A) RNA modification, in the pathogenesis of cerebrovascular diseases. Key m6A‑related genes, including the demethylases FTO and...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41466169
DOI: 10.1007/s11239-025-03230-y

Genes

FTO
ALKBH5
METTL3
METTL14
YTHDC1
YTHDF1
YTHDF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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