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Article

TPI1 promotes tumor progression and M2 macrophage polarization: Integrated pan-cancer and lung adenocarcinoma insights.

Biochemical and biophysical research communications - 25 Jan 2026

Liu Xuan, Gao Xiufeng, Ma Ranran, Wang Jing, Zha Tongtong, Huang Youming

Abstract excerpt

Triosephosphate isomerase 1 (TPI1), a glycolytic enzyme, has been increasingly implicated in cancer progression, yet its expression landscape across tumor types and functional roles in tumor immunity remain poorly defined. Here, we performed integrated pan-cancer analyses combining transcriptomic, proteomic, and single-cell RNA-sequencing datasets to characterize TPI1 expression, prognostic significance,...

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Share to Adenocarcinoma of Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41447883
DOI: 10.1016/j.bbrc.2025.153099

Genes

TPI1
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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