Article
Tumor-informed liquid biopsy for monitoring thyroid cancer: a proof-of-concept study.
European thyroid journal - 1 Feb 2026
Thomaz Debora Mota Dias, Rocha Welbert Gomes, Albuquerque Julia Cavallari, Viana Aline de Oliveira Ribeiro, Velloni Julia Maranhão Fagundes, Elen Costa da Silva Renata, Curioni Otavio Alberto, Callegari Fabiano Mesquita, Martins João Roberto Maciel, Mello Biscolla Rosa Paula, Cerutti Janete Maria
Abstract excerpt
Objective: This proof-of-concept, cross-sectional study assessed the feasibility and clinical relevance of detecting circulating tumor DNA (ctDNA) and RNA (ctRNA) in plasma of patients with thyroid cancer. The analysis was performed concurrently with clinical and biochemical assessment to explore its value as a complementary tool for postoperative surveillance. Methods: Thirty-four patients whose primary tumors...
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