Article
Impact of the quality of resected thyroid cancer tissue sample on next-generation sequencing testing.
Pathology international - 1 Feb 2024
Hatanaka Kanako C, Nakamura Kenichi, Katoh Ryohei, Ito Koichi, Hirokawa Mitsuyoshi, Miyauchi Akira, Matsuno Yoshihiro, Kano Satoshi, Okada Yui, Mori Joji, Ito Yoichi M, Hatanaka Yutaka
Abstract excerpt
Activating rearranged during transfection (RET) proto-oncogene alterations can be identified using next-generation sequencing (NGS) of tumor DNA/RNA. We assessed factors associated with NGS (Oncomine Dx Target Test [ODxTT]) success for resected thyroid cancer (TC) specimens, including sample age, processing conditions, and DNA/RNA quality. TC samples were from three Japanese hospitals, with sample age...
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