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Article

Clinical profiles associated with rapidly progressive interstitial lung disease in antisynthetase syndrome: A multicentric cohort study (TYPASS study).

Journal of internal medicine - 1 Mar 2026

Billotte Maxime, Moulinet Thomas, Meyer Alain, Camara Houda, Bolko Loïs, Didier Kévin, Dury Sandra, Bonnotte Bernard, Devilliers Hervé, Bonniaud Philippe, Beltramo Guillaume, Campagne Julien, Magy-Bertrand Nadine, Chaudier Aurore, Valentin Simon, Jaussaud Roland, Decker Paul

Abstract excerpt

OBJECTIVES: To assess factors associated with rapidly progressive interstitial lung disease (ILD) (RP-ILD) at time of ILD diagnosis in a multicentric retrospective cohort study of antisynthetase syndrome (ASyS). We used a complementary unsupervised approach, hierarchical clustering, to delineate distinct phenotypes among ASyS patients with ILD. METHODS: A total of 132 patients with ASyS, defined according to the...

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PMID: 41376133
DOI: 10.1111/joim.70058
PMCID: PMC12869006

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ACR

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