Article
Hierarchical cluster and survival analyses of antisynthetase syndrome: phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity.
Autoimmunity reviews - 1 Dec 2012
Hervier Baptiste, Devilliers Hervé, Stanciu Raluca, Meyer Alain, Uzunhan Yurdagul, Masseau Agathe, Dubucquoi Sylvain, Hatron Pierre-Yves, Musset Lucile, Wallaert Benoit, Nunes Hilario, Maisonobe Thierry, Olsson Nils-Olivier, Adoue Daniel, Arlet Philippe, Sibilia Jean, Guiguet Marguerite, Lauque Dominique, Amoura Zahir, Hachulla Eric, Hamidou Mohamed, Benveniste Olivier
Abstract excerpt
The clinical phenotype and evolution of antisynthetase syndrome (ASS) are heterogeneous. This study was therefore undertaken to identify subgroups of ASS patients with similar clinico-biological features and outcomes. This retrospective multicentric study included 233 consecutive patients with three different anti-aminoacyl-tRNA-synthetase antibodies (anti-ARS): anti-Jo1 (n=160), anti-PL7 (n=25) and anti-PL12...
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