Article
Clinical and molecular characterization of ILD in patients with overlapping ASyS and SjD: a retrospective observational study.
Rheumatology (Oxford, England) - 4 Feb 2026
Qiu Yulu, Lv Chengyin, Wang Yue, You Hanxiao, Wang Qi, Wang Fang, Tan Wenfeng, Zhu Yujing
Abstract excerpt
OBJECTIVE: Interstitial lung disease (ILD) is a frequent complication in both anti-synthetase syndrome (ASyS) and primary Sjögren's disease (pSjD), but the clinical and molecular phenotype of patients with overlapping ASyS and pSjD (ASyS-SjD) remains poorly defined. This study aimed to characterize the clinical, serological, radiological and transcriptomic features of ASyS-SjD patients with ILD, and to determine...
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