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Article

Deciphering the impact of genomic variation on function.

Nature - 1 Sept 2024

Abstract excerpt

Our genomes influence nearly every aspect of human biology-from molecular and cellular functions to phenotypes in health and disease. Studying the differences in DNA sequence between individuals (genomic variation) could reveal previously unknown mechanisms of human biology, uncover the basis of genetic predispositions to diseases, and guide the development of new diagnostic tools and therapeutic agents. Yet,...

Topics

Humans
Cells
Computer Simulation
Gene Expression Regulation
Gene Regulatory Networks
Genetic Association Studies
Genetic Predisposition to Disease
Genetic Variation
Genome, Human
Genomics
Models, Genetic
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Interaction Maps

Single-Cell Analysis

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Identifiers

PMID: 39232149
DOI: 10.1038/s41586-024-07510-0
PMCID: PMC11973978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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