Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Putative mitochondrial components of frontotemporal lobar degeneration: topological correlations between mitochondrial density and atrophy in FTLD/FTD phenotypes.

Journal of neurology - 8 Dec 2025

Tahedl Marlene, Kleinerova Jana, McKenna Mary Clare, Siah We Fong, Hardiman Orla, Hengeveld Jennifer C, Doherty Mark A, McLaughlin Russell L, Tan Ee Ling, Hutchinson Siobhan, Bede Peter

Abstract excerpt

BACKGROUND: Frontotemporal lobar degeneration encompasses a spectrum of clinically, radiologically, and molecularly heterogeneous conditions. Clinical phenotypes are defined based on predominant neuropsychological manifestations and the selective involvement of specific brain regions determines the core symptoms, disability profiles, and care needs. While the unique anatomical patterns of cortical and subcortical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Atrophy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frontotemporal Dementia

Share to Frontotemporal Lobar Degeneration

Share to Magnetic Resonance Imaging

Share to Mitochondria

Share to Phenotype

Source

Identifiers

PMID: 41354869
DOI: 10.1007/s00415-025-13552-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Putative mitochondrial components of frontotemporal lobar degeneration: topological correlations between mitochondrial density and atrophy in FTLD/FTD phenotypes.PMID 41354869Read ↗

Focal thalamus pathology in frontotemporal dementia: Phenotype-associated thalamic profiles.Semantic proximity Read ↗

Association of cortical and subcortical microstructure with disease severity: impact on cognitive decline, and language impairments in frontotemporal lobar degenerationSemantic proximity Read ↗

Frontotemporal lobar degeneration: clinical and pathological relationships.Semantic proximity Read ↗

Thalamic pathology in frontotemporal dementia: Predilection for specific nuclei, phenotype-specific signatures, clinical correlates, and practical relevance.Semantic proximity Read ↗

Infratentorial pathology in frontotemporal dementia: cerebellar grey and white matter alterations in FTD phenotypes.Semantic proximity Read ↗

Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degenerationSemantic proximity Read ↗

Frontotemporal lobar degeneration: Pathogenesis, pathology and pathways to phenotype.Semantic proximity Read ↗

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration.Semantic proximity Read ↗

Neuropathological background of phenotypical variability in frontotemporal dementia.Semantic proximity Read ↗

Cortical microstructure in familial frontotemporal dementia associated with MAPT, GRN, and C9orf72 pathogenic variants: Looking beyond atrophy.Semantic proximity Read ↗

Clinicopathological and genetic correlates of frontotemporal lobar degeneration and corticobasal degeneration.Semantic proximity Read ↗

Neuroimaging in frontotemporal lobar degeneration--predicting molecular pathology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.