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Article

Focal thalamus pathology in frontotemporal dementia: Phenotype-associated thalamic profiles.

Journal of the neurological sciences - 15 May 2022

McKenna Mary Clare, Li Hi Shing Stacey, Murad Aizuri, Lope Jasmin, Hardiman Orla, Hutchinson Siobhan, Bede Peter

Abstract excerpt

BACKGROUND: The clinical phenotypes of frontotemporal dementia (FTD) are defined by distinctive clinical features and associated with unique cortical atrophy patterns. Clinical manifestations in FTD however are not solely driven by cortical pathology, but stem from the selective dysfunction of corticobasal circuits, the majority of which are relayed through thalamic nuclei. The objective of this study is the...

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PMID: 35279595
DOI: 10.1016/j.jns.2022.120221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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