Article
Mendelian randomization analyses explore the causal relationship between fibroblast growth factor receptors and hypertrophic scar.
Growth factors (Chur, Switzerland) - 1 Oct 2025
Ma Hong-Fang, Shen Jun
Abstract excerpt
During the formation of hypertrophic scars (HS), there is often a notable abnormal proliferation and differentiation of cells, especially fibroblasts, but it remains ambiguous whether a causal relationship exists between fibroblast growth factor receptors (FGFRs) and hypertrophic scar. This study explored the causal impact of FGFR1, FGFR2, FGFR3, and FGFR4 on HS utilizing a two-sample Mendelian randomization (MR)...
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