Characteristics of Group A Streptococcus M1 and Non-M1 Isolates from Adult and Pediatric Populations in Central Japan, 2024-2025: sic Nucleotide Alleles with CovS Amino Acid Mutations in M1 Clones.

Abstract excerpt

We aimed to specify the characteristics of group A Streptococcus M1 (n = 23) or non-M1 (n = 282) isolates from adult (n = 176) and pediatric (n = 129) populations in central Japan, October 2024-April 2025. Of the 14 speA-possessing non-M1 isolates, there were seven emm3.93 isolates from 6 non-invasive samples of pediatric patients and 1 invasive specimen of an adult patient. We found the distribution of M1 clones...

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