Article
Emerging Invasive Group A Streptococcus M1UK Lineage Detected by Allele-Specific PCR, England, 20201.
Emerging infectious diseases - 1 May 2023
Zhi Xiangyun, Li Ho Kwong, Li Hanqi, Loboda Zuzanna, Charles Samson, Vieira Ana, Huse Kristin, Jauneikaite Elita, Reeves Lucy, Mok Kai Yi, Coelho Juliana, Lamagni Theresa, Sriskandan Shiranee
Abstract excerpt
Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK. An allele-specific PCR was developed to distinguish M1UK from other emm1 strains. The M1UK lineage represented 91% of invasive emm1 isolates in England in 2020. Allele-specific PCR will permit surveillance for M1UK without need for genome sequencing.
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