Article
Genetic diversity and evolutionary adaptation of Clostridium paraputrificum, a rare pathogen in humans.
Communications biology - 29 Nov 2025
Liu Jiao, Chen Yizhu, Du Hangxiang, Yang Lechen, Xu Zhuofei, Wen ZhenLiang, Shang Weifeng, Pan Xiaojun, Zhang Lidi, Cui Yunliang, Chen Dechang, Zhang Sheng
Abstract excerpt
Clostridium paraputrificum infection in humans is extremely rare, and its pathogenesis and evolutionary mechanisms remain poorly understood. We sequenced the genome of strain CP_SH01 isolated from the blood culture of an ICU patient with acute abdominal injury and bloodstream infection. The genome harbored an intact prophage and ten insertion-sequence elements. Genome-wide metabolic reconstruction uncovered 42...
Topics
Join the communities discussing this publication.