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Phylogenetic and genomic analysis reveals high genomic openness and genetic diversity of Clostridium perfringens.

Microbial genomics - 1 Oct 2020

Feng Yuqing, Fan Xuezheng, Zhu Liangquan, Yang Xinyue, Liu Yan, Gao Shiguang, Jin Xiaolu, Liu Dan, Ding Jiabo, Guo Yuming, Hu Yongfei

Abstract excerpt

Clostridium perfringens is associated with a variety of diseases in both humans and animals. Recent advances in genomic sequencing make it timely to re-visit this important pathogen. Although the genome sequence of C. perfringens was first determined in 2002, large-scale comparative genomics with isolates of different origins is still lacking. In this study, we used whole-genome sequencing of 45 C. perfringens...

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PMID: 32975504
DOI: 10.1099/mgen.0.000441
PMCID: PMC7660258

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