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Article

CHD8 -Related Neurodevelopmental Disorder Manifesting Adult-Onset Compulsive Behaviors.

Clinical genetics - 1 Apr 2026

Lan Shih-Chun, Lan Min-Yu, Chang Yung-Yee, Huang Yu-Chi

Abstract excerpt

A patient of intellectual developmental disorder with autism and macrocephaly (IDDAM) caused by a novel CHD8 mutation developed adult-onset compulsive behaviors in addition to the core phenotype in early life. This case expands the clinical and genotypic spectrums of IDDAM which may inspire future studies on genotype-phenotype correlation and the disease course.

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Source

Identifiers

PMID: 41309157
DOI: 10.1111/cge.70117

Genes

CHD8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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