Coriobacteriia may affect the occurrence of hepatocellular carcinoma through the pyrimidine, caffeine, urea cycle and glutamate metabolic pathways.

Abstract excerpt

Most patients with hepatocellular carcinoma (HCC) lose the chance of survival due to lack of timely diagnosis and effective treatment. The specific gut microbiota (GM) spectrum may become the target of early diagnosis and treatment of HCC. However, the metabolic mechanisms that affect the occurrence of liver cancer are still unclear. In this study, we called the dataset of HCC, and 1091 serum metabolites 309...

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