Article
Association of gut microbiome and primary liver cancer: A two-sample Mendelian randomization and case-control study.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2023
Ma Jun, Li Jialiang, Jin Chen, Yang Jinhuan, Zheng Chongming, Chen Kaiwen, Xie Yitong, Yang Yi, Bo Zhiyuan, Wang Jingxian, Su Qing, Wang Juejin, Chen Gang, Wang Yi
Abstract excerpt
BACKGROUND AND AIMS: Observational epidemiology studies suggested a relationship between the gut microbiome and primary liver cancer. However, the causal relationship remains unclear because of confounding factors and reverse causality. We aimed to explore the causal role of the gut microbiome in the development of primary liver cancer, including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma...
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