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Laboratory validation of a clinical metagenomic next-generation sequencing assay for respiratory virus detection and discovery

12 Nov 2024

Abstract excerpt

Tools for rapid identification of novel and/or emerging viruses are urgently needed for clinical diagnosis of unexplained infections and pandemic preparedness. Here we developed and clinically validated a largely automated metagenomic next-generation sequencing (mNGS) assay for agnostic detection of respiratory viral pathogens from upper respiratory swab and bronchoalveolar lavage samples in <24 h. The mNGS assay...

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PMID: 39532844
DOI: 10.1038/s41467-024-51470-y

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