Article
Association of metabolomics measurements with blood cell phenotypes.
Blood cells, molecules & diseases - 1 Mar 2026
Chen Brian D, Tapia Amanda, Boerwinkle Eric, Clish Clary B, Gerszten Robert, Graff Misa, Mohlke Karen L, Morrison Alanna C, Pathmasiri Wimal, Rich Stephen S, Rotter Jerome I, Rushing Blake R, Sumner Susan, Tracy Russell P, Young Kristin L, Yu Bing, Thyagarajan Bharat, Reiner Alex P, Li Yun, Raffield Laura
Abstract excerpt
Complete blood counts (CBCs) are commonly measured in clinical practice and are associated with different diseases and traits. Statistical adjustment for blood cell abundance or related traits in these metabolomic epidemiology studies is not a common practice. However, it is plausible that common and cheaply measured blood cells would capture some of the variation also captured by metabolomic measures. Here, we...
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