Urinary cell cycle arrest proteins for early prediction and phenotyping of subclinical and clinical acute kidney injury after liver transplantation.

doi:10.1097/LVT.0000000000000755

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Article

Urinary cell cycle arrest proteins for early prediction and phenotyping of subclinical and clinical acute kidney injury after liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 May 2026

Scaravilli Vittorio, Bosone Marco, Turconi Gloria, Bonetti Claudia, Cappelli Francesca, Cirillo Ginevra, Di Pellegrino Sofia, Ferrari Fiorenza, Colombo Sebastiano Maria, Lozio Federico, Caccamo Lucio, Castellano Giuseppe, Dondossola Daniele Eliseo, Zanella Alberto, Grasselli Giacomo

Abstract excerpt

Acute kidney injury (AKI) is common after liver transplantation, but difficult to diagnose with serum creatinine and urinary output. This study evaluated the early risk stratification capability of urinary tissue inhibitor of metalloproteinases-2 and insulin-like growth factor binding protein-7 (u[TIMP-2]*[IGFBP-7]) in a prospective adult liver transplantation cohort. u[TIMP-2]*[IGFBP-7] was measured 6 and 36...

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PMID: 41289017
DOI: 10.1097/LVT.0000000000000755

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