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Article

Biomarker-based acute kidney injury sub-phenotypes refine risk assessment in children undergoing cardiac surgery.

Pediatric nephrology (Berlin, Germany) - 1 Feb 2025

Pettit Kevin A, Melink Katherine F, Alten Jeffrey A, Goldstein Stuart L, Ollberding Nicholas, SooHoo Megan, Sullivan Emily, Zang Huaiyu, Stanski Natalja L, Gist Katja M

Abstract excerpt

BACKGROUND: Pediatric cardiac surgery-associated acute kidney injury (CS-AKI) is common with variable association with outcomes, possibly because transient serum creatinine (SCr) elevations are unrelated to kidney disease. Sub-phenotypes of CS-AKI with biomarker integration may provide prognostic enrichment. This study aims to determine if combining early postoperative urine neutrophil gelatinase-associated...

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Acute Kidney Injury
Biomarkers
Cardiac Surgical Procedures
Creatinine
Infant, Newborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Postoperative Complications

Risk Assessment

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PMID: 39331076
DOI: 10.1007/s00467-024-06541-z

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