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Mutations in the clpS Gene of Riemerella anatipestifer Affect Stress Response and Bacterial Virulence.

Current microbiology - 24 Nov 2025

Yufu Liu, Jiayi Liu, Ruixin Liao, Fang Rong, Yuanwen Deng, Tao Long, Ladi Li, Xueyi Cheng, Sainan Li, Zhengliang Ouyang, Wenhua Liu, Ruiai Chen

Abstract excerpt

The Clp protease regulates antibiotic resistance, biofilm formation, stress response, and virulence in microorganisms through a post-transcriptional mechanism. Substrate recognition by the ClpS subunit is essential for the target protein degradation. However, the function of ClpS in Riemerella anatipestifer (R. anatipestifer) remains unclear. In this study, a clpS gene (B739_1609) in-frame deletion strain of R....

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PMID: 41283912
DOI: 10.1007/s00284-025-04618-y

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