Article
The functional identification of Dps in oxidative stress resistance and virulence of Riemerella anatipestifer CH-1 using a new unmarked gene deletion strategy.
Veterinary microbiology - 1 Aug 2020
Tian Xiu, Huang Li, Wang Mingshu, Biville Francis, Zhu Dekang, Jia Renyong, Chen Shun, Zhao Xinxin, Yang Qiao, Wu Ying, Zhang Shaqiu, Huang Juan, Zhang Ling, Yu Yanling, Cheng Anchun, Liu Mafeng
Abstract excerpt
Excessive iron in the bacterial cytoplasm can potentiate the production of harmful reactive oxygen species (ROS). Riemerella anatipestifer (R. anatipestifer, RA), a gram-negative bacterium, encodes an iron uptake system, but its iron detoxification mechanism is unknown. Here, the dps gene of R. anatipestifer CH-1 (RA-CH-1) was deleted using sacB as a counterselection marker. The dps mutant was more sensitive to...
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