Article
Disruption of the M949_RS01915 gene changed the bacterial lipopolysaccharide pattern, pathogenicity and gene expression of Riemerella anatipestifer.
Veterinary research - 6 Feb 2017
Dou Yafeng, Wang Xiaolan, Yu Guijing, Wang Shaohui, Tian Mingxing, Qi Jingjing, Li Tao, Ding Chan, Yu Shengqing
Abstract excerpt
Riemerella anatipestifer is an important pathogen that causes septicemia anserum exsudativa in ducks. Lipopolysaccharide (LPS) is considered to be a major virulence factor of R. anatipestifer. To identify genes involved in LPS biosynthesis, we screened a library of random Tn4351 transposon mutants using a monoclonal antibody against R. anatipestifer serotype 1 LPS (anti-LPS MAb). A mutant strain RA1067 which lost...
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