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Article

Dietary patterns, polygenic risk, and kidney cancer incidence: a UK Biobank cohort study.

Journal of translational medicine - 19 Nov 2025

Zou Mingrui, Deng Ruiyi, Qiu Jianhui, Mao Kaiyuan, Shang Jiaheng, Zhu Sainan, Cai Lin, Wang Yizhou, Gong Kan, Zhou Jingcheng

Abstract excerpt

BACKGROUND: Diet and genetic risk are established risk factors for kidney cancer, but their interaction remains unclear. This study aims to systematically investigate the associations between various dietary patterns and kidney cancer risk, as well as to evaluate the combined effects of diet and genetic risk on kidney cancer risk. METHODS: We conducted a prospective cohort study involving 113,594 participants...

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Identifiers

PMID: 41257832
DOI: 10.1186/s12967-025-07373-7
PMCID: PMC12628948

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