Hypertensive disorders of pregnancy, maternal cardiovascular disease mortality and the role of familial predisposition: a Norwegian population-based sibling-comparison, sibling-spillover and negative-control cohort study.

Abstract excerpt

Hypertensive disorders of pregnancy (HDP) are associated with increased maternal cardiovascular disease (CVD) mortality, with risks varying by HDP subtypes and subsequent pregnancy outcomes. The contribution of shared familial factors given this heterogeneity is unclear. We conducted a population-based study using Norwegian registries (1967-2020) including 1 106 658 women with complete pregnancy histories, of...

Topics

• Humans
• Female
• Norway
• Pregnancy
• Siblings
• Cardiovascular Diseases
• Adult
• Hypertension, Pregnancy-Induced
• Registries
• Pre-Eclampsia
• Genetic Predisposition to Disease