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Article

Novel Phenotypic Clusters of Youth-Onset Type 2 Diabetes Offer No Added Prognostic Value to Simple Clinical Measures.

Diabetes care - 1 Jan 2026

Kreienkamp Raymond J, Smith Kirk, Wangden Thinley Yidzin, Deutsch Aaron J, Gage Steven D, Bellatorre Anna, Dabelea Dana M, D'Agostino Ralph B, Dolan Lawrence M, Florez Jose C, Jensen Elizabeth T, Pihoker Catherine, Pollin Toni I, Shah Amy S, Szczerbinski Lukasz, Udler Miriam S, Srinivasan Shylaja

Abstract excerpt

OBJECTIVE: Clinical heterogeneity in youth-onset type 2 diabetes is less understood than that of adult-onset type 2 diabetes. We performed phenotypic clustering of youth-onset type 2 diabetes to determine whether clusters provided clinical utility. RESEARCH DESIGN AND METHODS: We performed data-driven clustering in a diverse subset of autoantibody-negative, clinician-diagnosed type 2 diabetes before age 20 years...

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Share to Adolescent
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41237324
DOI: 10.2337/dc25-1765
PMCID: PMC12719710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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