Article
Causal effects of 731 immune cells on post-traumatic stress disorder: A Mendelian randomization study.
Medicine - 17 Oct 2025
Tan Jie, Bai Siyang, Hu Gang, Yin Yuman, Guo Chenlu, Liu Liang
Abstract excerpt
The involvement of immune cells in the pathogenesis of post-traumatic stress disorder (PTSD) remains incompletely understood. This study aims to evaluate the causal effect of immune cells on PTSD by Mendelian randomization (MR). Datasets of 731 immune cells, numbered from GCST0001391 to GCST0002121, were obtained from European Bioinformatics Institute, and datasets of PTSD, numbered finngen_R10_F5_PTSD, were...
Read the complete abstract on PubMedTopics
- Humans
- Mendelian Randomization Analysis
- Stress Disorders, Post-Traumatic
- Polymorphism, Single Nucleotide
- Genetic Predisposition to Disease
