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Article

A Mendelian randomization study: causal relationship between immune cells and the risks of social phobia, specific phobia, and agoraphobia.

BMC psychiatry - 8 Apr 2025

Wang Jun-Neng, Yu Dong-Hu, Li Zhi-Yu, Kong Ling-Yue, Li Nan-Hao, Wu You-Xian, Wang Tian-Qing, Wang Ze-Fen, Li Zhi-Qiang

Abstract excerpt

BACKGROUND: Although phobia is a common psychiatric disorder, the underlying biological mechanisms have not been fully elucidated. Complex immune-brain interactions that affect neural development, survival, and function may have causal and therapeutic implications in psychiatric illnesses. In this study, the relationships between immune cell traits and phobia were analysed using Mendelian randomization to explore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40200188
DOI: 10.1186/s12888-025-06794-4
PMCID: PMC11980060

Genes

CD28
CD33
CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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