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Article

Physical Activity and Favorable Adiposity Genetic Liability Reduce the Risk of Hypertension Among High Body Mass Individuals.

Journal of the American Heart Association - 4 Nov 2025

Hezekiah Chukwueloka, Pazoki Raha

Abstract excerpt

BACKGROUND: Hypertension is a global health issue, and the risk factors include genetics, physical inactivity, and excess body fat (adiposity). Genetic predisposition to adiposity generally increases risk of hypertension. Several genetic variants have been identified to increase adiposity but unexpectedly reduce hypertension (favorable adiposity genes). Here, we tested the effect of these genetic variants on risk...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41128150
DOI: 10.1161/JAHA.124.040701
PMCID: PMC12684782

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