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Article

The Role of Mesenchymal Stem Cells in Drug Resistance in Lung Neoplasms

5 Sept 2025

Abstract excerpt

The tumor microenvironment (TME) is a decisive determinant of therapeutic response and the emergence of drug resistance in lung cancer. Among its stromal constituents, mesenchymal stem cells (MSCs) are pivotal regulators of disease progression because they secrete diverse paracrine mediators. Accumulating evidence indicates that MSC-derived cytokines, growth factors, and extracellular vesicles (EVs) drive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 41112422
DOI: 10.15430/jcp.25.015

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