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Article

Association of ABCA4 gene polymorphisms with nonsyndromic cleft lip with or without cleft palate in a case-parent trio study.

Journal of stomatology, oral and maxillofacial surgery - 1 Feb 2026

Ansari Mohammad Ashraf, Kumar K Vinod, Parida Bishnu Prasad, Chauhan Anjali, Narayan Gopeshwar, Singh Subodh Kumar

Abstract excerpt

BACKGROUND: Nonsyndromic cleft lip and/or palate (NSCL/P) is a common congenital craniofacial anomaly with multifactorial etiology. Several genome-wide association studies (GWAS) have implicated polymorphisms in ABCA4 gene in correlation to NSCL/P. We conducted a trio-based SNP analysis to evaluate the role of rs560426 and rs4147811 in NSCL/P pathogenesis in an Indian population. METHODS: Blood samples were...

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Source

Identifiers

PMID: 41109678
DOI: 10.1016/j.jormas.2025.102626

Genes

ABCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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