Article
Further evidence suggesting a role for variation in ARHGAP29 variants in nonsyndromic cleft lip/palate.
Birth defects research. Part A, Clinical and molecular teratology - 1 Sept 2014
Letra Ariadne, Maili Lorena, Mulliken John B, Buchanan Edward, Blanton Susan H, Hecht Jacqueline T
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect of complex etiology. Several genes have been implicated in the etiology of NSCL/P, although only a few have been replicated across datasets. METHODS: ARHGAP29 was suggested as a candidate gene for NSCL/P as it is located in close proximity to ABCA4 (1p22), a gene previously identified in a genome-wide association...
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