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Article

Integrative Mendelian Randomization and Transcriptomic Analysis Reveal the Causal Association between Psoriatic Arthritis and Uveitis.

The Journal of investigative dermatology - 1 May 2026

Hao Junfeng, Chu Mengyang, Ma Jiaojiao, Xu Guangquan, Li Qingyang, Li Bing, Dang Erle, Luo Yixin, Sun Zhongbin, Xu Zhongrui, Li Zhiguo, Xiao Chunying, Wang Hua, Xue Ke, Shao Shuai, Wang Gang

Abstract excerpt

Psoriatic arthritis (PsA) is a chronic inflammatory condition often associated with uveitis in clinical practice. However, the causal relationship between these diseases and their underlying mechanisms of interaction remain unclear. Therefore, our objective was to investigate the cause-effect relationships between PsA and uveitis and explore the association between the 2 diseases. The MR analysis revealed an OR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41101629
DOI: 10.1016/j.jid.2025.09.374

Genes

BAK1
FKBPL
ZKSCAN4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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