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Article

SMARCA4 pathogenic variants: Gynecological cancer histories from a laboratory tested cohort.

Gynecologic oncology - 1 Nov 2025

Borden Brittany A, Rodriguez-Hernandez Adela, Trottier Magan, Horiguchi Miki, Weyandt Jamie D, Horton Carolyn, Polfus Linda M, Bychkovsky Brittany L, Young Colin C, Garber Judy E, St Laurent Jessica D, Rana Huma Q

Abstract excerpt

OBJECTIVE: To describe the cancer histories of individuals with a SMARCA4 germline pathogenic/likely pathogenic variant (gPV) obtained through clinical laboratory-based testing to aid in informing guidance surrounding surveillance and prevention for individuals with gPV. METHODS: This retrospective cohort study analyzed individuals with a SMARCA4 gPV identified by multigene panel testing for hereditary cancer at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41086671
DOI: 10.1016/j.ygyno.2025.10.001

Genes

SMARCA4

Provenance

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