Article
Immunological biomarkers and molecular signatures in healthy aging: early dynamics of subclinical atherosclerosis in a homogeneous elderly cohort.
BMC cardiovascular disorders - 13 Oct 2025
Weyh Christopher, Bauer Pascal, Größer Vincent Walter, Zhupani Danja, Cemic Franz, Huber Magdalena, Raifer Hartmann, Mahnke Marius, Frech Torsten, Böttrich Tim, Gebhardt Kristina, Nolte Svenja, Reichel Thomas, Sommer Natascha, Ringseis Robert, Eder Klaus, Krüger Karsten
Abstract excerpt
BACKGROUND: The study aimed to investigate early immunological and molecular changes in a homogeneous group of healthy older individuals, initially screened to categorize them into groups with or without subclinical carotid artery plaque. Subsequently, immunological and molecular signatures, vascular health parameters, and lifestyle factors were assessed, and a comprehensive bioinformatics analysis was conducted...
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