Gene-elusive arrhythmogenic cardiomyopathy: Roles of sports, inflammation, and beyond.

Abstract excerpt

Arrhythmogenic cardiomyopathy (ACM) represents a leading cause of sudden cardiac death in young adults and in athletes. Although inherited cases typically involve genetic variants in desmosomal proteins, impairing cardiac tissue's capacity to withstand mechanical stress, approximately one-third of patients with ACM harbor no identifiable genetic variant and are classified as gene elusive. Even if some...

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