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Article

TET2 mutations in myeloproliferative neoplasms: potential mediation of atrial fibrillation by interleukin-1β and impact on stroke risk in clinical cohorts.

Journal of thrombosis and haemostasis : JTH - 1 Jan 2026

Teng Guangshuai, Duan Minghui, Shang Ke, Zhang Yuhui, Wei Xiaojing, Peng Lan, Tse Gary, Zhou Yuan, Lip Gregory Y H, Liu Tong, Bai Jie

Abstract excerpt

BACKGROUND: The role of clonal hematopoiesis of indeterminate potential (CHIP) related gene mutations in atrial fibrillation (AF) and stroke in patients with myeloproliferative neoplasms (MPNs) remains insufficiently investigated. OBJECTIVES: To investigate the role of CHIP related gene mutations in AF and stroke in patients with MPNs and explore the role of cytokines. METHODS: A retrospective cohort of 465 MPN...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41077132
DOI: 10.1016/j.jtha.2025.09.015

Genes

TET2
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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TET2 mutations in myeloproliferative neoplasms: potential mediation of atrial fibrillation by interleukin-1β and impact on stroke risk in clinical cohorts.PMID 41077132Read ↗

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