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Article

Causal effects of sleep behaviors on temporomandibular disorders and pain: a bidirectional mendelian randomization study.

Journal of oral & facial pain and headache - 1 Jun 2025

Zhang Yuxiao, Ozathaley Ahsawle, Wang Xiangyao, Wu Yaxin, Zhang Kehan, Li Yuanyuan, Nuerlan Gaoshaer, Li Qilin, Mao Jing, Li Haosen, Gong Shiqiang

Abstract excerpt

BACKGROUND: Temporomandibular disorder (TMD) is a prevalent condition associated with pain and dysfunction of the temporomandibular joint (TMJ) and surrounding structures. Sleep disturbances are common in TMD patients, yet the bidirectional causal relationship between specific sleep behaviors and TMD remains unclear. This study aimed to investigate this relationship using a two-sample Mendelian randomization (MR)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41070538
DOI: 10.22514/jofph.2025.029
PMCID: PMC12531579

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