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Article

CRISPR-based platforms for detecting tumor-associated genetic materials in clinical samples.

Bioanalysis - 1 Oct 2025

Chen Xiaoqing, Ye Qiaoyuan, Liang Qingle, Li Jiahui, Huang Yumei, Xia Qiyuan, Xiao Jianrong, Liao Chenyu, Lau Cia-Hin, Zhu Haibao

Abstract excerpt

Tumor-associated genetic markers are useful for early cancer screening, diagnosis, and treatment monitoring. However, traditional detection methods are complex in operation procedures, time-consuming, and the equipment costs are expensive. CRISPR/Cas systems are becoming emerging detection tools for tumor detection due to their programmability, rapid reaction, high targeting specificity, and the ability to...

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PMID: 41064997
DOI: 10.1080/17576180.2025.2571023
PMCID: PMC12667656

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