Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women.

BMC women's health - 29 Sept 2025

Zhu Jiamin, Yang Baixia, Zhai Xiaogang, Ni Feng, Tao Dan, Tan Cheng

Abstract excerpt

OBJECTIVES: the aim of this study was to evaluate the impact of TLR4 gene single nucleotide polymorphisms (SNPs) and additional TLR4 gene SNP- SNP and SNP- abdominal obesity (AO) interaction on ovarian cancer (OC) risk. METHODS: Generalized multifactor dimensionality reduction method were utilized to identify the most informative interactions between four SNPs in the TLR4 gene and abdominal obesity. Logistic...

Read the complete abstract on PubMed

Topics

Adult
Female
Humans
Middle Aged
Alleles
Case-Control Studies
China

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genotype

Logistic Models

Obesity, Abdominal

Ovarian Neoplasms

Polymorphism, Single Nucleotide

Risk Factors

Toll-Like Receptor 4

East Asian People

Source

Open in PubMed Open full text

Identifiers

PMID: 41023971
DOI: 10.1186/s12905-025-04001-w
PMCID: PMC12481797

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women.PMID 41023971Read ↗

An updated systematic review of the association between the TLR4 polymorphism rs4986790 and cancers risk.Semantic proximity Read ↗

The Toll-like Receptor 4 Polymorphism Asp299Gly Is Associated with an Increased Risk of Ovarian Cancer.Semantic proximity Read ↗

Gene-gene interaction between PPARδ and PPARγ is associated with abdominal obesity in a Chinese population.Semantic proximity Read ↗

Polymorphisms of the TLR4 gene and risk of gastric cancer.Semantic proximity Read ↗

The TLR4 gene polymorphisms and susceptibility to cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

Interaction between CYP1A1 gene polymorphism and environment factors on risk of endometrial cancer.Semantic proximity Read ↗

Impact of Toll-like receptor 4 polymorphisms on risk of cancer.Semantic proximity Read ↗

Interaction between XRCC2 gene polymorphism and abdominal obesity on risk of endometrial carcinoma.Semantic proximity Read ↗

Association of single-nucleotide polymorphisms in TLR4 gene and gene-environment interaction with primary open angle glaucoma in a Chinese northern population.Semantic proximity Read ↗

Disparities in Characteristics, Symptoms and mtDNA Influence on Ovarian Cancer Patients From South Indian PopulationSemantic proximity Read ↗

Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors.Semantic proximity Read ↗

[Effects of PPARD-87T > C and interactions with single nucleotide polymorphisms in PPARA and PPARG on abdominal obesity].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.