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Article

Spectrum of genetic variants detected in children tested for long QT syndrome.

BMC cardiovascular disorders - 26 Sept 2025

Kemezyte Aurelija, Meskiene Raimonda, Utkus Algirdas, Burnyte Birute

Abstract excerpt

BACKGROUND: Long QT syndrome (LQTS) is one of the most common inherited cardiac arrhythmias associated with sudden cardiac death worldwide. Despite the widespread implementation of next-generation sequencing, its diagnostic value remains limited due to challenges in interpreting the clinical significance of the identified variants. Since LQTS is rare and underreported in Baltic region, studies on small...

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Identifiers

PMID: 41013213
DOI: 10.1186/s12872-025-05118-4
PMCID: PMC12465144

Genes

KCNQ1

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