A Distinctive DICER1-Related Wilms-Like Uterine Tumor: A Report of Eight Cases.

doi:10.1016/j.modpat.2025.100895

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Article

A Distinctive DICER1-Related Wilms-Like Uterine Tumor: A Report of Eight Cases.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2025

Turashvili Gulisa, Croce Sabrina, Davidson Ben, Hausladen Silke, Solheim Olesya, Carinelli Silvestro, Lombardi Mariano, Lim Diana, Devins Kyle, Lin Lawrence Hsu, Dias-Santagata Dora, Young Robert H, Oliva Esther

Abstract excerpt

The presence of DICER1 mutations associated with overlapping morphologic features in tumors arising at different sites has been suggested to define an emerging category of DICER1-related neoplasms. We undertook a clinicopathologic and molecular characterization of uterine tumors originally diagnosed as Wilms tumors to ascertain if they belong to the spectrum of DICER1-related neoplasms. Of 8 patients with a...

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Topics

Humans
Female
Ribonuclease III
DEAD-box RNA Helicases
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Uterine Neoplasms

Wilms Tumor

Adolescent

Aged

Young Adult

Mutation

Biomarkers, Tumor

Source

Open in PubMed

Identifiers

PMID: 40998289
DOI: 10.1016/j.modpat.2025.100895

Genes

DICER1
KRAS

Provenance

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