Article
Targeting the PINK1/Parkin pathway: A new perspective in the prevention and therapy of diabetic retinopathy
6 Aug 2024
Abstract excerpt
Diabetic retinopathy (DR) is a microvascular complication of diabetes characterized by neurovascular impairment of the retina. The dysregulation of the mitophagy process occurs before apoptotic cell death and the appearance of vascular damage. In particular, mitochondrial alterations happen during DR development, supporting the hypothesis that mitophagy is negatively correlated to disease progression. This...
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