Gangliosides and Neuroblastomas

doi:10.3390/ijms21155313

Article

Gangliosides and Neuroblastomas

27 Jul 2020

Abstract excerpt

The focus of this review is the ganglio-series of glycosphingolipids found in neuroblastoma (NB) and the myriad of unanswered questions associated with their possible role(s) in this cancer. NB is one of the more common solid malignancies of children. Five-year survival for those diagnosed with low risk NB is 90-95%, while that for children with high-risk NB is around 40-50%. Much of the survival rate reflects...

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