Article
Risk of melanoma among people with BRCA1 and BRCA2 pathogenic variants: A systematic review and meta-analysis.
Gynecologic oncology - 1 Oct 2025
Frontera Nicole M, Ahsan Muhammad Danyal, Chandler Isabelle R, Levi Sarah R, Brewer Jesse T, Weiss Jessica M, Ma Xiaoyue, Jewell Sarah T, Sharaf Ravi N, Frey Melissa K
Abstract excerpt
BACKGROUND: Patients with BRCA1/2 pathogenic gene variants (PGVs) have an increased risk for breast, ovarian, pancreatic, and prostate cancer, with emerging evidence suggesting an association with melanoma. We aim to evaluate the strength of the melanoma association to guide cancer risk-management recommendations. METHODS: This systematic review and meta-analysis is reported in accordance with the Preferred...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.