Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inherited Predispositions to Myeloid Neoplasms: Pathogenesis and Clinical Implications

2 Oct 2024

Abstract excerpt

Myeloid neoplasms with and without preexisting platelet disorders frequently develop in association with an underlying germline predisposition. Germline alterations affecting ANKRD26 , CEBPA , DDX41 , ETV6 , and RUNX1 are associated with nonsyndromic predisposition to the development of myeloid neoplasms including acute myeloid leukemia and myelodysplastic syndrome. However, germline predisposition to myeloid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Blood disorders and treatments
Share to Myeloproliferative Neoplasms: Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39357070
DOI: 10.1146/annurev-pathmechdis-111523-023420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inherited Predispositions to Myeloid Neoplasms: Pathogenesis and Clinical ImplicationsPMID 39357070Read ↗

Germline predisposition to myeloid neoplasms: Characteristics and management of high versus variable penetrance disorders.Semantic proximity Read ↗

Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.Semantic proximity Read ↗

Germline predispositions to myeloid malignancies: Across the lifespan.Semantic proximity Read ↗

Germline Variants and Characteristic Features of Hereditary Hematological Malignancy SyndromeSemantic proximity Read ↗

Germline Variants and Characteristic Features of Hereditary Hematological Malignancy SyndromeSemantic proximity Read ↗

[Myeloid neoplasms with germline predisposition].Semantic proximity Read ↗

Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.Semantic proximity Read ↗

Hereditary Predisposition to Hematopoietic Neoplasms: When Bloodline Matters for Blood Cancers.Semantic proximity Read ↗

Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults.Semantic proximity Read ↗

Pediatric Germline Predisposition to Myeloid Neoplasms.Semantic proximity Read ↗

Cancer predisposition syndromes associated with myeloid malignancy.Semantic proximity Read ↗

Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-upSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.