Article
Genomewide association study of a homogeneous multiple sclerosis cohort: Tumefactive demyelination.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Sept 2025
Zhao-Fleming Hannah H, Decker Paul A, Kosel Matthew L, Drucker Kristen L, Kollmeyer Thomas, Lachance Daniel H, Clarkson Benjamin D, Howe Charles L, Jenkins Robert, Tobin W Oliver, Eckel-Passow Jeanette
Abstract excerpt
BACKGROUND: Tumefactive demyelination (TD) is a rare variant of multiple sclerosis (MS) characterized by tumor-like lesions that often require aggressive management. Genome-wide association studies (GWAS) identified variants associated with MS; similar analyses in TD are lacking. OBJECTIVE: A GWAS was performed to identify variants associated with TD. METHODS: The case-control study included 142 TD cases and 293...
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- Humans
- Genome-Wide Association Study
- Male
- Female
- Multiple Sclerosis